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Colorex 0157 with Cefixime & Tellurite This medium replaces the conventional Sorbitol MacConkey Agar that is reputed for high levels of false positives and the difficulty of colonial interpretation and differentiation. Colorex O157 is a chromogenic medium with a very high specificity (98% according to K.A. Bettelheim, 1998 J.Appl.Microbiol.85:425-428) for E.coli O157. To reduce the level of background flora, the medium is made selective by the addition of Cefixime and Potassium tellurite. Positive colonies exhibit a mauve colouration enabling easy interpretation amongst blue or colourless colonies of other bacteria. -
Colorex™ mSuperCARBA™ ™ is a selective and differential chromogenic culture medium, intended for use in the qualitative direct detection of gastrointestinal colonization with carbapenem-resistant Enterobacteria (CRE). CPE/CPO stands for Carbapenemase Producing Enterobacteriaceae / Carbapenemase Producing Organism. This group of bacteria, e.g., E. coli, Klebsiella spp. and Enterobacter spp., are highly resistant to antibiotics (including carbapenems). Colorex™ mSuperCARBA™ was designed to simplify the detection of CPEs, including the “Big Five” such as OXA-48 like enzymes in Enterobacterales, allowing for improved monitoring of high-risk patient groups. The distinctive colony colouration produced by different species can allow for a presumptive positive result to be assessed within 24 hours of receipt of the specimen. Typical colour reactions are as follows:Organism Expected colour CPE E.coli Dark pink to reddish CPE Escherichia coli Metallic blue CPO Klebsiella pneumoniae Translucent, +/- natural pigmentation cream to green CPO Enterococcus faecalis Cream Other Gram (-) CPO Colourless, natural pigmentation Non-CPE E. coli/Coliforms Inhibited Other Gram (-) non-CPO Inhibited Gram (+) bacteria Inhibited -
Vancomycin-resistant Enterococcus (VRE) infections are especially aggressive and have been associated with mortality rates approaching 60% to 70%. They are now the second-leading cause of nosocomial infections in the U.S., and their prevalence is increasing worldwide. Resistance to vancomycin has the potential to be transferred from bacteria to bacteria. Cross-resistance is mediated by plasmids and transposons, which may transfer the genes associated with resistance to other much more aggressive pathogens, such as staphylococci and streptococci. Three principal types of vancomycin resistance are found in Enterococcus spp.; VanA, VanB and VanC genotypes. VanA and VanB types account for most significant infections in clinical settings, involving E.faecium and E.faecalis. VanC resistance is a low-level intrinsic resistance found in other Enterococcus spp. The Colorex™ VRE media is another chromogenic media in the Colorex™ range, enabling presumptive identification of vancomycin resistant Enterococci by the formation of mauve/pink coloured colonies (for VanA and VanB genotypes) and blue coloured colonies (for VanC genotypes) after 18-24 hours incubation.
